PRMT4 (CARM1) Mouse Monoclonal Antibody [Clone ID: 3H2]

Specifications

Product Data
Clone Name	3H2
Applications	ELISA, FC, IF, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow Cytometry: 1/200 - 1/400. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human, Monkey, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human CARM1 expressed in E. Coli.
Specificity	Recognizes CARM1
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	65 kDa
Gene Name	coactivator associated arginine methyltransferase 1
Database Link	Entrez Gene 10498 Human UniProt ID Q86X55
Background	Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
Synonyms	PRMT4
Reference Data

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