GRK2 Mouse Monoclonal Antibody [Clone ID: 3F8]

Specifications

Product Data
Clone Name	3F8
Applications	ELISA, IF, IHC, WB
Recommend Dilution	Western Bloting: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000.
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human GRK2 expressed in E. Coli.
Specificity	This antibody reacts to GRK2.
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	80 kDa
Gene Name	G protein-coupled receptor kinase 2
Database Link	Entrez Gene 156 Human UniProt ID P25098
Background	The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes
Synonyms	BARK, BARK1, GRK2, Beta-adrenergic receptor kinase 1
Reference Data

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