GLUR3 (GRIA3) Mouse Monoclonal Antibody [Clone ID: 1D2]

Specifications

Product Data
Clone Name	1D2
Applications	ELISA, IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human GRIA3 expressed in E. Coli.
Specificity	This antibody reacts to GRIA3.
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	101 kDa
Gene Name	glutamate ionotropic receptor AMPA type subunit 3
Database Link	Entrez Gene 2892 Human UniProt ID P42263
Background	Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Synonyms	GluR-3, GluR-C, GluR-K3, Glutamate receptor ionotropic AMPA3, GRIA3, GLURC, GluA3
Reference Data

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