SRC Mouse Monoclonal Antibody [Clone ID: 1F11]

Specifications

Product Data
Clone Name	1F11
Applications	ELISA, FC, IHC, WB
Recommend Dilution	ELISA: 1/10000. Flow Cytometry: 1/200-1/400. Western Blot: 1/500-1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human SRC expressed in E. Coli.
Specificity	This antibody recognizes Human SRC. Other species not tested.
Isotype	IgG1
Formulation	State: Ascites State: Liquid Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	60 kDa
Gene Name	SRC proto-oncogene, non-receptor tyrosine kinase
Database Link	Entrez Gene 6714 Human UniProt ID P12931
Background	This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Synonyms	c-Src, pp60c-src
Reference Data

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