LRP5 Mouse Monoclonal Antibody [Clone ID: 2B11]

Specifications

Product Data
Clone Name	2B11
Applications	ELISA, FC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human LRP5 expressed in E. Coli.
Specificity	Recognizes LRP5
Isotype	IgG1
Formulation	PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 0.5% protein stabilizer Preservative: 0.05% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	179 kDa
Gene Name	LDL receptor related protein 5
Database Link	Entrez Gene 4041 Human UniProt ID O75197
Background	This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Synonyms	LRP7, LRP-5
Reference Data

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