Cd28 Hamster Monoclonal Antibody [Clone ID: 37.51]

Specifications

Product Data
Clone Name	37.51
Applications	FC, FN, IP
Recommend Dilution	Flow Cytometry. (Ref.2-5) Immunoprecipitation. (Ref.2) Functional Assay: In vitro costimulation of T cells and NK cells. (Ref.1,4,7)
Reactivity	Mouse
Host	Hamster
Clonality	Monoclonal
Specificity	This antibody is specific to CD28 costimulatory receptor (Mr. 40 kDa)
Isotype	IgG
Formulation	PBS containing no preservatives. State: Low Endotoxin State: Liquid purified Ig fraction.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	CD28 antigen
Database Link	Entrez Gene 12487 Mouse UniProt ID P31041
Background	CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4) CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.5-8)
Synonyms	TP44
Reference Data

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