Cd79b Hamster Monoclonal Antibody [Clone ID: HM79-12]

Specifications

Product Data
Clone Name	HM79-12
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2) Immunoprecipitation. (Ref.1) Immunohistochemistry on Frozen Sections. (Ref.3) Western Blotting. (Ref.1)
Reactivity	Mouse
Host	Hamster
Clonality	Monoclonal
Specificity	This antibody recognises beta chain of the mouse B-cell receptor (Mr. 23 kDa).
Isotype	IgG
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD79B antigen
Database Link	Entrez Gene 15985 Mouse UniProt ID P15530
Background	Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (Ref.1)
Synonyms	B29, IGB, B-Cell marker
Reference Data

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