PGP9.5 (UCHL1) Mouse Monoclonal Antibody [Clone ID: 3D9]

Specifications

Product Data
Clone Name	3D9
Applications	ELISA, ICC/IF, IF, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/1,000-1/2,000. Flow Cytometry. Immunofluorescence/Immnunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/100-1/200.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PGP9.5 (1-223aa) purified from E. coli
Specificity	The antibody recognizes Human and Mouse PGP9.5. Other species not tested.
Isotype	IgG2a, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	ubiquitin C-terminal hydrolase L1
Database Link	NP_004172 Entrez Gene 7345 Human UniProt ID P09936
Background	PGP9. 5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9. 5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9. 5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
Synonyms	Ubiquitin C-terminal hydrolase L1, Ubiquitin carboxyl-terminal esterase L1, Ubiquitin thiolesterase L1, Parkinson Disease 5, PARK5, PGP9.5, Uch-L1, UCHL-1, Neuron cytoplasmic protein 9.5
Reference Data

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