TREM2 Mouse Monoclonal Antibody [Clone ID: 2B5]

Specifications

Product Data
Clone Name	2B5
Applications	ELISA, FACS, ICC/IF, WB
Recommend Dilution	ELISA. Western blot (1/500-1/1,000).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human TREM2 (19-161aa) purified from E. coli
Specificity	The antibody recognizes Human and Mouse TREM2. Other species not tested.
Isotype	IgG3, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	triggering receptor expressed on myeloid cells 2
Database Link	NP_061838 Entrez Gene 54209 Human UniProt ID Q9NZC2
Background	The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system).
Synonyms	Ttriggering receptor expressed on myeloid cells 2 isoform 1, Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on myeloid cells 2a, TREM-2, Trem2a, Trem2b, Trem2c
Reference Data

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