CRABP2 Mouse Monoclonal Antibody [Clone ID: AT2E11]

Specifications

Product Data
Clone Name	AT2E11
Applications	ELISA, ICC/IF, IHC, WB
Recommend Dilution	ELISA. Western blot (1/250-1/1,000). Immunohistochemistry on Paraffin Sections (10 µg/ml). This CRABP2 antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) Human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human CRABP2 (1-138aa) purified from E. coli
Specificity	The antibody recognizes Human and Mouse CRABP2. Other species not tested.
Isotype	IgG2a, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	cellular retinoic acid binding protein 2
Database Link	NP_001869 Entrez Gene 12904 MouseEntrez Gene 1382 Human UniProt ID P29373
Background	The cellular retinoic acid-binding protein II (CRABP-II) is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus.
Synonyms	Cellular retinoic acid binding protein 2, RBP6, CRABP-II, Cellular retinoic acid binding protein 2, CRABP2, RBP6, CRABP-II, Cellular retinoic acid binding protein 2 Cellular retinoic acid binding protein II, CRABP II, CRABPII
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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