Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: 165]

Specifications

Product Data
Clone Name	165
Applications	ELISA, WB
Recommend Dilution	ELISA: Reacts with IFN-gamma at 0.1 ng/ml dilution of monoclonal antibody. Western Blot: IFN gamma antibody (AM09168PU-N) used at a concentration of 0.5 µg/ml, will allow visualization of 100 ng/lane of Interferon gamma.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant Human Interferon gamma (IFN gamma).
Specificity	This antibody recognizes both, recombinant and native human IFN-gamma.
Isotype	IgG1
Formulation	0.01M PBS, pH 7.0 without preservatives. State: Aff - Purified State: Lyophilized purified IgG fraction.
Reconstitution Method	Restore with double distillated water is recommended and to adjust the final concentration to 1.00 mg/ml
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	interferon, gamma
Database Link	Entrez Gene 3458 Human UniProt ID P01579
Background	Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.
Synonyms	IFN-gamma, gamma IFN
Note	Myeloma: Sp2/0-Ag14
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus

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