CRLF2 Mouse Monoclonal Antibody [Clone ID: 8H8]

Specifications

Product Data
Clone Name	8H8
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/20000-1/100000. Western Blot: 1/2000-1/10000. Immunohistochemistry on Paraffin Sections: 10 µg/ml after heat induced antigen retrieval.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human TSLP R /Fc chimera
Specificity	Reacts with Human 42 kDa TSLP Receptor
Isotype	IgG1
Formulation	PBS State: Purified State: Lyophilized powder Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	cytokine receptor-like factor 2
Database Link	Entrez Gene 64109 Human UniProt ID Q9HC73
Background	TSLPR is a 42 kDa glycoprotein belonging to the type 1 cytokine receptor family. TSLPR is primarily expressed by dendritic cells and monocytes, and weakly expressed by T-cells. It is also expressed by non-haematopoietic tissues such as the heart, skeletal muscle, kidney and liver. The TSLP receptor forms functional complexes with thymic stromal lymphopoietin (TSLP) and IL-7R, which are capable of stimulating cell proliferation through activation of Stat3 and Stat5.
Synonyms	Cytokine receptor-like 2, IL-XR, ILXR, TSLPR
Reference Data

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