Sumo 3 (SUMO3) Mouse Monoclonal Antibody [Clone ID: 76AT630.91.31]

Specifications

Product Data
Clone Name	76AT630.91.31
Applications	WB
Recommend Dilution	ELISA: 1/1,000. Western blot: 1/100-1/500.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant GST-SUMO3 fusion protein
Specificity	This antibody is specific to SUMO3.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	small ubiquitin-like modifier 3
Database Link	Entrez Gene 6612 Human UniProt ID P55854
Background	Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.
Synonyms	SUMO-3, SMT3 homolog 1, SMT3H1
Reference Data

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