IL23 (IL23A) Mouse Monoclonal Antibody [Clone ID: HLT2736]

CAT#: AM20386PU-N

IL23 (IL23A) mouse monoclonal antibody, clone HLT2736, Purified



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CNY 5,511.00


货期*
5周

规格
    • 50 ug

Cited in 3 publications.

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Specifications

Product Data
Clone Name HLT2736
Applications IHC, WB
Recommend Dilution Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Western Blot.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human IL23A / IL23 protein
Specificity Detects Human recombinant p40 and p19 with elastin linker.
Formulation PBS, pH 7.2, sourced in TCS
State: Purified
State: Liquid purified Ig fraction
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
Gene Name interleukin 23 subunit alpha
Background The p19 shares sequence similarity with IL-6 subfamily members and is distantly related to the p35 subunit of IL-12. It shows no biological activity by itself; instead, it combines with the p40 subunit of IL-12 to form a biologically active, composite cytokine, IL-23. IL-23 shares some in vivo functions with IL-12, including the activation of the transcription factor Stat4. Similar to IL-12, human IL-23 stimulates IFN-g production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.
Synonyms IL-23 subunit alpha, SGRF, Interleukin-23 subunit p19, IL-23p19
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (3)

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