Collagen IV (COL4A1) Mouse Monoclonal Antibody [Clone ID: Col-30]

Specifications

Product Data
Clone Name	Col-30
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin and frozen sections: 0.5 - 1 μg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human collagen type IV
Specificity	This antibody reacts to Collagen type IV.
Isotype	IgG1
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1 ml of 1.2% sodium acetate or neutral PBS
Concentration	0.1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	collagen type IV alpha 1 chain
Database Link	Entrez Gene 1282 Human UniProt ID P02462
Background	Collagen IV is comprised of a third chain (alpha-3) together with the 2 classical ones, alpha-1 and alpha-2. COL4A3 gene is localized to 2q36-q37 by analysis of somatic cell hybrids and by in situ hybridization. The alpha-3 chain of type IV collagen induces autoimmune Goodpasture syndrome.Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria.
Synonyms	COL4A1
Reference Data
Protein Pathways	ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

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