alpha 1 Spectrin (SPTA1) Mouse Monoclonal Antibody [Clone ID: Spe 1/2]

Specifications

Product Data
Clone Name	Spe 1/2
Applications	WB
Recommend Dilution	Western Blot: 2 - 4 μg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human erythrocyte spectrin
Specificity	This antibody reacts to Spectrin (erythrocyte) (alpha / beta).
Isotype	IgG1
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	spectrin alpha, erythrocytic 1
Database Link	Entrez Gene 6708 Human UniProt ID P02549
Background	Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2.Spectrin mutations cause spinocerebellar ataxia type 5.
Synonyms	SPTA, Erythroid alpha-spectrin
Reference Data

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