Tryptophan Hydroxylase (TPH1) Mouse Monoclonal Antibody [Clone ID: Try-63]

Specifications

Product Data
Clone Name	Try-63
Applications	WB
Recommend Dilution	Western Blot: 0.5 - 1 μg/ml.
Reactivity	Human, Rabbit, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant rabbit tryptophan hydroxylase
Specificity	This antibody reacts to Tryptophan 5-hydroxylase 1.
Isotype	IgG3
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	tryptophan hydroxylase 1
Database Link	Entrez Gene 24848 RatEntrez Gene 7166 Human UniProt ID P17752
Background	Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine,or 5HT). Tryptophan hydroxylaseatalyzes the iopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase (TPH) is mapped to chromosome 11p15.3-p14 by in situhybridization.
Synonyms	Tryptophan 5-monooxygenase 1, TPRH, TRPH
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Tryptophan metabolism

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