HCV NS5B RdRp (111-130) Mouse Monoclonal Antibody [Clone ID: 9A2]

Specifications

Product Data
Clone Name	9A2
Applications	ELISA, IF, IP, WB
Recommend Dilution	Reacts in ELISA, Western blot and Immunoprecipitation with genotype 1b (con-1) HCV NS5B protein. ELISA: 1/1000. Western blot (reduced conditions): 1/1000. Immunofluorescence: 1/500.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Hepatitis C Virus nonstructural protein 5B (NS5B) RNAdependent RNA polymerase (RdRp)
Specificity	This antibody detects Hepatitis C virus NS5B-protein (aa 111-130). Human, HCV subtype 1b NS5B, Epitope mapped to amino acids 111-130 (LSSKAVNHIRSVWKDLLEDT).
Isotype	IgG1
Formulation	PBS pH 7.4 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Protein G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20 to -70°C. Avoid repeated freezing and thawing.
Background	Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.
Synonyms	Hepatitis C Virus, RNA-directed RNA polymerase NS5B
Reference Data

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