HLA Class II DR Mouse Monoclonal Antibody [Clone ID: EDU-1]

Specifications

Product Data
Clone Name	EDU-1
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on Frozen Sections: 0.1 µg/ml (1/2000). Suggested Positive Control: Human tonsil. Has been described to work in FACS.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes HLA DR antigen.
Isotype	IgG2b
Formulation	Phosphate buffered saline pH 7.2 (PBS) Label: Biotin State: Lyophilized purified Ig fraction Stabilizer: 5 mg/ml BSA Preservative: 0.05 % (v/v) Kathon CG
Reconstitution Method	Restore by adding 0.5ml distilled water.
Concentration	0.2 mg/ml (after reconstitution)
Purification	Affinity Chromatography
Conjugation	Biotin
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Background	HLA DR antigen is an HLA class II antigen with homology to murine H-2E. HLA-DR is an αβ heterodimer. The N-terminal domain of the mature protein forms an alpha-helix that constitutes the exposed part of the binding groove, the C-terminal cytoplasmic region interacts with the other chain forming a beta-sheet under the binding groove spanning to the cell membrane.
Synonyms	HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR
Note	Antigen distribution: Isolated cells: Antigen presenting cells (macrophages, B-cells and dendritic cells) are the cells in which DR are typically found.
Reference Data

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