TNFRSF1B Mouse Monoclonal Antibody [Clone ID: MR2-1]

Specifications

Product Data
Clone Name	MR2-1
Applications	ELISA, FC, FN, IHC, IP, WB
Recommend Dilution	Immunohistochemistry on frozen sections: The typical starting working dilution is 1:10. Positive control: Human lymphnodes. Flow cytometry: The typical starting working dilution is 1:10. Positive control: PHA activated T cells. Functional assays. Immunoassays. Immunoprecipitation. Western blot: The typical starting working dilution is 1:10. The monoclonal antibody MR2-1 is an agonistic antibody (after cross-linking) and receptor modulating antibody. The reactivity of the antibody MR2-1 with cell-bound TNF-Receptor is minimally inhibited by high concentrations of TNF-alpha.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Specificity	The antibody MR2-1 reacts with the extra-cellular part of the TNF-RII. It also reacts with the soluble receptor.
Isotype	IgG1
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin
Concentration	lot specific
Purification	Protein G
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Gene Name	tumor necrosis factor receptor superfamily member 1B
Database Link	Entrez Gene 7133 Human UniProt ID P20333
Background	TNF-RII is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-RII molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha.
Synonyms	Tumor necrosis factor receptor 2, p80 TNF-alpha receptor, TNFRSF1B, TNFBR, TNF-R2
Note
Reference Data

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