Ethenoadenosine Mouse Monoclonal Antibody [Clone ID: 1G4]

Specifications

Product Data
Clone Name	1G4
Applications	ELISA, IHC, IP, WB
Recommend Dilution	Immunohistochemistry on frozen sections. Flow cytometry. Immunoassays. Immunoprecipitation. Western blot.
Host	Mouse
Clonality	Monoclonal
Specificity	The monoclonal antibody 1G4 reacts with both the ribose and deoxyribose form of the adduct. It is not cross reactive with non-modified DNA or the normal nucleotides.
Isotype	IgG2a
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein G
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Background	The reaction of chloroacetaldehyde (CAA) with DNA results in the formation of ethenoadenosine also known as 1,N6-ethenodeoxy-adenosine or etheno-A. CAA is formed through metabolization of for example vinyl chloride, a well established carcinogen. In RNA, after in vitro activation, etheno-A and etheno-C are the principle products of RNA damage. Etheno derivate formation may be highest in single-stranded DNA-regions.
Synonyms	1,N6-ethenodeoxy-adenosine
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.