GPCR MRGX2 (MRGPRX2) Mouse Monoclonal Antibody [Clone ID: 1D3]

Specifications

Product Data
Clone Name	1D3
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin sections: 1 µg/ml (1/200). Positive control: Human pancreas.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	DNA vaccine
Specificity	This antibody detects Human MRGPRX2 (GPCRx11).
Isotype	IgG2b
Formulation	Phosphate buffered saline pH 7.2 (PBS) State: Purified State: Lyophilized affinity purified Ig fraction Stabilizer: 5 mg/ml bovine serum albumin (BSA) Preservative: 0.09% sodium azide
Reconstitution Method	Reconstitute by adding 0.5ml distilled water.
Concentration	0.2 mg/ml (after reconstitution)
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	MAS related GPR family member X2
Database Link	Entrez Gene 117194 Human UniProt ID Q96LB1
Background	MRGPRX2 or cortistatin receptor is a 330 amino acid protein that belongs to the G - protein coupled receptor 1 family. Mas - related G - protein - coupled receptors (Mrgprs) represent a large family of orphan receptors specifically expressed in small - diameter nociceptive primary sensory neurons. Physiological functions include mediation of itch or regulat ion of persistent pathological pain. Cortistatin - 14, which is involved in sleep regulation, locomotor activity, and cortical function, seems to be a high potency ligand at this receptor. Also, the multifunctional antibacterial protein LL - 37 has been shown to activate cells presumably through MRGPRX2.
Synonyms	MRGX2
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.