OPA1L (WBP1L) (152-342) Mouse Monoclonal Antibody [Clone ID: OPAL1-01]

Specifications

Product Data
Clone Name	OPAL1-01
Applications	FC, WB
Recommend Dilution	Flow cytometry (intracellular staining): Recommended dilution: 1-4 µg/ml. Western blot: Recommended dilution: 1-2 μg/ml, non-reducing conditions.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant fragment of human OPAL1 (amino acids 152-342)
Specificity	This antibody recognizes OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.
Isotype	IgG2a
Formulation	Tris buffered saline (TBS) State: Purified State: Liquid ig fraction Preservative: 15 mM sodium azide, approx. pH 8.0
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	WW domain binding protein 1-like
Database Link	Entrez Gene 54838 Human UniProt ID Q9NX94
Background	OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.
Synonyms	C10orf26, OPA1L, Outcome predictor in acute leukemia 1
Reference Data

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