IL9R Mouse Monoclonal Antibody [Clone ID: AH9R7]

Specifications

Product Data
Clone Name	AH9R7
Applications	ELISA, FC, FN
Recommend Dilution	Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CD129-transfected cell line
Specificity	This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
Isotype	IgG2b
Formulation	Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 μm filter sterilized State: Low Endotoxin State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	interleukin 9 receptor
Database Link	Entrez Gene 3581 Human UniProt ID Q01113
Background	CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
Synonyms	Interleukin-9 receptor, IL-9R, IL-9 receptor
Reference Data

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