TNFRSF4 Mouse Monoclonal Antibody [Clone ID: Ber-ACT35]

Specifications

Product Data
Clone Name	Ber-ACT35
Applications	ELISA, FC, IHC, IP, WB
Recommend Dilution	Flow cytometry. Immunoprecipitation Western blot. Immunohistochemistry (paraffin sections). Immunohistochemistry (frozen sections). ELISA.
Reactivity	Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	HTLV 1-transformed HUT-102 cells
Specificity	This antibody clone Ber-ACT35 (also known as ACT35) recognizes CD134 (TNFRSF4, OX40), an approximately 50 kDa type I transmembrane glycoprotein expressed on activated T cells.
Isotype	IgG1
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	tumor necrosis factor receptor superfamily member 4
Database Link	Entrez Gene 7293 Human UniProt ID P43489
Background	CD134 (TNFRSF4, also known as OX40) is a type I transmembrane glycoprotein of TNF/NGF receptor family expressed on activated T cells, fibroblasts, and hematopoietic precursors. Binding to its ligand (OX40L, TNFSF4) on antigen presenting cells gives to the T cell costimulatory signal, and this interaction results also in B cell proliferation and influences T cell memory pool. CD134 is upregulated at sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions.
Synonyms	TNFRSF4, TXGP1L, ACT35 antigen, OX40L receptor
Reference Data

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