D-Dimer Mouse Monoclonal Antibody [Clone ID: DD1]

Specifications

Product Data
Clone Name	DD1
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Homogenised fibrin clot. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
Specificity	This antibody is specific for Human D-dimer and high molecular weight Fibrin Degradation Products, but does not cross-react with Fibrinogen (D-monomer). By Western Blot (non-reducing conditions) this antibody detect the 180 kD D-dimer.
Isotype	IgG2a
Formulation	PBS containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.
Synonyms	Fibrin breakdown product, Fibrinogen Degradation Product D
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.