Factor VII (F7) (+VIIa) Mouse Monoclonal Antibody [Clone ID: AA-3]

Specifications

Product Data
Clone Name	AA-3
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Factor VII (AA-3) purified from plasma.
Specificity	This antibody is specific for factor VII/VIIa (AA-3).
Isotype	IgG1
Formulation	PBS Label: Biotin State: Liquid purified IgG fraction Stabilizer: EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml Preservative: 0.02% Sodium Azide
Concentration	lot specific
Conjugation	Biotin
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	coagulation factor VII
Database Link	Entrez Gene 2155 Human UniProt ID P08709
Background	Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the first EGF-like domain of factor VII/VIIa. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.
Synonyms	Proconvertin, SPCA
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Complement and coagulation cascades

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