IL24 Mouse Monoclonal Antibody [Clone ID: B-C54]

Specifications

Product Data
Clone Name	B-C54
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human IL-24. Myeloma X63/AG.8653 x Balb/c node cells.
Specificity	This Monoclonal antibody recognises both natural and recombinant Human IL-24 (Interleukin-24) also known as MDA-7 or TH2-specific cytokine FISP.
Isotype	IgG2a
Formulation	PBS without carriers and preservatives State: Azide Free State: Liquid purified (0.2 μm sterile filtered) IgG fraction
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	interleukin 24
Database Link	Entrez Gene 11009 Human UniProt ID Q13007
Background	Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Synonyms	IL-24, MDA7, ST16
Reference Data

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