Park7 Mouse Monoclonal Antibody [Clone ID: 4H4]

Specifications

Product Data
Clone Name	4H4
Applications	IF, WB
Recommend Dilution	Western blotting: 1/2000.  Immunofluorescence: 1/500.
Reactivity	Bovine, Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length recombinant human park7 expressed in and purified from E. coli.
Specificity	This antibody is specific for the ~21k park7 protein.
Formulation	PBS State: Purified State: Liquid purified IgG fraction from Culture Supernatant Preservative: 10 mM Sodium Azide
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	Parkinsonism associated deglycase
Database Link	Entrez Gene 117287 Rat UniProt ID O88767
Background	Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).
Synonyms	Oncogene DJ1, Parkinson disease protein 7
Reference Data

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