Apolipoprotein A I (APOA1) (25-267) Mouse Monoclonal Antibody [Clone ID: AT1E12]

Specifications

Product Data
Clone Name	AT1E12
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: (1/500-1/5,000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human APOA1 (25-267aa) purified from E. coli
Specificity	The antibody recognizes Human APOA1. Other species not tested.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	apolipoprotein A1
Database Link	NP_000030.1 Entrez Gene 335 Human UniProt ID P02647
Background	Apolipoprotein A1 (APOA1) is the main protein component of high density lipoprotein (HDL) in plasma. This protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in APOA1 are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. High level of APOA1 is regarded as protective against atherosclerosis and cardiovascular disease.
Synonyms	APOA1, apolipoprotein A-I, Apolipoprotein A1, Apo-AI, ApoA-I
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	PPAR signaling pathway

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