AKR7A3 Mouse Monoclonal Antibody [Clone ID: AT2E11]

Specifications

Product Data
Clone Name	AT2E11
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot (1:1000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human AKR7A3 (1-331aa) purified from E. coli
Specificity	The antibody recognizes human AKR7A3. Other species not tested.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
Database Link	AAH25709 Entrez Gene 22977 Human UniProt ID O95154
Background	Aldo-keto reductase family 7, member A 3 (AKR7A3) is a member of the aldo/keto reductase superfamily involved in the detoxification and metabolism of a variety of exogenous aldehydes and ketones. The activity of AKR7A3 may detoxify the aflatoxin B1 (AFB1) dialdehyde, which reacts with proteins, and thereby inhibitis AFB1 induced toxicity. AKR7A3 is expressed in kidney, colon, pancreas, endometrium and adenocarcinoma.
Synonyms	Aldo-keto reductase family 7 member A 3, Aflatoxin B1 aldehyde reductase member 3, AFB1 aldehyde reductase 2(AFAR2), AFB1 AR 2, Aflatoxin aldehyde reductase, Aflatoxin B1 aldehyde reductase 2
Reference Data
Protein Families	Druggable Genome

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