CRLF2 Mouse Monoclonal Antibody [Clone ID: AT4E7]

Specifications

Product Data
Clone Name	AT4E7
Applications	ELISA, FACS, WB
Recommend Dilution	The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000. Recommended starting dilution is 1:1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human CRLF2 (23-231aa) purified from E. coli
Isotype	IgG2a, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	cytokine receptor-like factor 2
Database Link	NP_071431 Entrez Gene 64109 Human UniProt ID Q9HC73
Background	CRLF2 is cytokine receptor-like factor 2. Cytokine signals are mediated through specific receptor complexes, the components of which are mostly members of the type I cytokine receptor family. Type I cytokine receptors share conserved structural features in their extracellular domain. Receptor complexes are typically heterodimeric, consisting of alpha chains, which provide ligand specificity, and beta (or gamma) chains, which are required for the formation of high-affinity binding sites and signal transduction.
Synonyms	Cytokine receptor-like factor 2 isoform 1 precursor, CRL2, CRLF2Y, TSLPR, Cytokine receptor-like factor 2 isoform 1, CRLF2, Cytokine receptor-like 2, ILXR, Thymic stromal lymphopoietin protein receptor, TSLP receptor
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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