Collagen V (COL5A1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Immunoblotting. Immunofluorescence. Immunohistochemistry on frozen sections.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Human type V collagen
Specificity	This antibody reacts to Collagen V. This antibody shows less than 10% reactivity with collagen type I, II, III, IV, and VI. It may react with collagen V from other species. Reactivity with other ECM proteins has not been tested.
Formulation	Borate buffered saline State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	collagen type V alpha 1
Database Link	Entrez Gene 1289 Human UniProt ID P20908
Background	Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.
Synonyms	COL5A1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	ECM-receptor interaction, Focal adhesion

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