PDE5A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	Western blot. Immunohistochemistry. Immunoprecipitation.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Designed from the C-terminal region common to the 5A isoform.
Specificity	The antibody selectively detects proteins corresponding to the PDE5A.
Formulation	State: Serum State: Liquid diluted serum
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphodiesterase 5A
Database Link	Entrez Gene 8654 Human UniProt ID O76074
Background	Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE5 enzyme belongs to a family of cGMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cGMP.
Synonyms	PDE5, cGMP-specific 3',5'-cyclic phosphodiesterase, EC=3.1.4.35, cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE
Reference Data

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