Renin (REN) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/50000. Western blot: 1/5,000. Immunohistochemistry: 1/1,000.
Reactivity	Mouse, Rat
Host	Sheep
Clonality	Polyclonal
Immunogen	Recombinant Rat Prorenin
Specificity	This antibody reacts with Rat and Mouse Renin. Other species not tested.
Formulation	0.05M Sodium Phosphate, 0.1M Sodium Chloride, 1mM EDTA, pH 6.6 State: Purified State: Liquid purified Ig fraction Preservative: None
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing.
Gene Name	renin
Database Link	UniProt ID P00797
Background	Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Renin also occurs in other organs than the kidney, e.g., in the brain, where it is implicated in the regulation of numerous activities.
Synonyms	REN, Angiotensinogenase, angiotensin-forming enzyme, HNFJ2
Reference Data

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