Phospholipase C gamma 1 (PLCG1) pTyr783 Rabbit Polyclonal Antibody

CAT#: AP02395PU-S

Phospholipase C gamma 1 (PLCG1) pTyr783 rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 1,400.00


货期*
2周

规格
    • 50 ul

Product images

Specifications

Product Data
Applications WB
Recommend Dilution Western blot: 1/500-1/1000.
Incubate membrane with diluted antibody in 5% nonfat milk, 1xTBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of Tyrosine 783 (G-F-YP-V-E) derived from Human PLC-gamma-1 .
Specificity This antibody detects endogenous levels of PLC-gamma 1 only when phosphorylated at Tyrosine 783.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol
State: Aff - Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography using using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site
Conjugation Unconjugated
Storage Condition Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Gene Name phospholipase C gamma 1
Background Phospholipase C gamma (PLCG) binds to receptor tyrosine kinases, e.g. EGFR, PDGFR, leading to phosphorylation of PLC-gamma at Tyrosine 771, 783 and 1245. Phosphorylation of Tyrosine 783 leads to enzymatic activation of PLC-gamma. PLC-gamma hydrolyzes phosphatidylinostitol-4,5-bisphosphate (PIP2), thus generating the second messengers inostitol-1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
Synonyms PLC1, Phospholipase C-gamma-1, PLC-gamma-1, PLC gamma1 Phospholipase C-II, PLC-II, PLC-148
Note Molecular Weight: 155 kDa
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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