PPP2R5C Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: Detects a 56 kDa band. Positive Control: Whole rat brain homogenate.
Reactivity	Bovine, Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Antibody raised against synthetic peptide corresponding to amino acids 53 to 66 of the mammalian protein phosphatase 2 A/B conjugated to KLH.
Specificity	This antibody reacts to Protein phosphatase 2A (PP2A).
Isotype	IgG
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2 µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	protein phosphatase 2 regulatory subunit B'gamma
Database Link	Entrez Gene 26931 MouseEntrez Gene 691318 RatEntrez Gene 5527 Human UniProt ID Q13362
Background	Protein phosphatase 2A (PP2A) is a hetertrimeric enzyme consisting of a catalytic subunits (C), a structural subunit (A) and a variable regulatory subunit (B). The B subunit family is made up of the a, b and g isoforms. The PP2A/Bg isoform appears to only be detectable in the brain where it has been speculated that it cytoskeletal substrates. The RNA which produces the PP2A/Bg is developmentally regulated and increases sharply after birth. It has also been suggested that it may be important in the establishment and maintenance of neuronal connections.
Synonyms	Protein phosphatase 2A, PP2A B subunit B' gamma isoform, PP2A B subunit B56 gamma isoform, PP2A B subunit PR61 gamma isoform, PP2A B subunit R5 gamma isoform, KIAA0044, NY-REN-29
Reference Data
Protein Families	Druggable Genome, Phosphatase
Protein Pathways	Oocyte meiosis, Wnt signaling pathway

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