PP2A-alpha (PPP2CA) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	IP, WB
Recommend Dilution	Immunoblotting: 1:500 to 1:1,000. Immunoprecipitation often used in combination with affinity purified anti-pp2A/A to immunoprecipitate hetrotrimeric pp2A. Immunocytochemistry 1:1,000.
Reactivity	Bovine, Human, Mouse, Rat
Host	Sheep
Clonality	Polyclonal
Immunogen	A peptide conjugated to KLH
Specificity	This antibody reacts to serine/threonine protein phosphatase 2A/C.
Isotype	IgG
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	protein phosphatase 2 catalytic subunit alpha
Database Link	Entrez Gene 19052 MouseEntrez Gene 24672 RatEntrez Gene 5515 Human UniProt ID P67775
Background	The immunogen used to the purified peptide conjugated to KLH corresponding to the sequence NH2-Pro-His-Val-Thr-Arg-Arg-Thr-Pro-Asp-Tyr-Phe-Leu-COOH. This peptide antibody corresponds to C -terminal peptide of PP2A/C catalytic subunit having a MW of 36kDa. The sequence used is amino acid 298 - 309.
Synonyms	Protein Phospatase 2A, PP2A-alpha, Replication protein C
Reference Data
Protein Families	Druggable Genome, Phosphatase, Transcription Factors
Protein Pathways	Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway

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