TOB (TOB1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1-5 µg/ml. Positive Control: HeLa cell lysate.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from the TOB protein
Specificity	This antibody recognizes TOB1.
Isotype	IgG
Formulation	Phosphate buffered saline with 0.08% Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	transducer of ERBB2, 1
Database Link	Entrez Gene 10140 Human UniProt ID P50616
Background	Rabbit anti-human TOB (Transducer Molecule of erbB-2) reacts with a 45 kDa protein originally identified as a molecule that interacts with the ErbB-2 protein, a receptor protein tyrosine kinase (RPTK). TOB does not contain either SH2 or SH3 domains but is homologous with the N terminus of the anti-proliferative BTG-1 protein. Like BTG-1, TOB when exogenously expressed, is able to suppress the growth of NIH3T3 cells. This growth suppression is hindered by the presence of kinase-active p185erbB2.
Synonyms	TOB, TROB1
Reference Data

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