PPAP2C (PLPP2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Western Blot. Enzyme Immunoassay.
Reactivity	Human, Porcine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from the lipid phosphate phosphohydrolase 2 protein
Specificity	This antibody reacts to Lipid Phosphate Phosphohydrolase 2.
Isotype	IgG
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Aff - Purified State: Liquid purified Ig
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Ship on dry ice. Store (in aliquots) at -20°C to -70°C. Avoid repeated freezing and thawing.
Gene Name	phospholipid phosphatase 2
Database Link	Entrez Gene 8612 Human UniProt ID O43688
Background	Phosphatidic acid (PA), lysophosphatidic acid, ceramide 1-phosphate (C1P), and sphingosine 1-phosphate (S1P) are lipid mediators generated by phospholipases, sphingomyelinases, and lipid kinases. The major pathway for degradation of these lipids is dephosphorylation catalyzed by members of two classes (types 1 and 2) of phosphohydrolase activities (PAPs). cDNAs encoding two type 2 PAPs, PAP-2a and -2b, have been expressed by transient transfection and shown to catalyze hydrolysis of PA, C1P, and S1P.
Synonyms	PAP2-gamma
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transmembrane
Protein Pathways	Ether lipid metabolism, Fc gamma R-mediated phagocytosis, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Sphingolipid metabolism

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