IL32 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 5 - 10 µg/ml; detects a band/s of approximately 26kDa in jurkat cell lysate.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 16 amino acid peptide located near the centre of human IL-32.
Specificity	This antibody recognises IL-32.
Isotype	IgG
Formulation	Phosphate buffered saline containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for up to one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	interleukin 32
Database Link	Entrez Gene 9235 Human UniProt ID P24001
Background	IL-32 is a 26 kDa cytokine, thought to play a role in innate and adaptive immune responses. IL-32 is produced by mitogen-activated lymphocytes, interferon-gamma activated epithelial cells and IL-12, IL-18, IL-32-activated NK cells. It is expressed at elevated levels after the activation of T-cells by mitogens or the activation of NK cells by IL-2. IL-32 activates NF-kappa-B and p38 MAPK cytokine signal pathways. TNF-alpha, IL-1beta, IL-6 and 2 C-X-C chemokine family members, all involved in autoimmune and inflammatory diseases, including rheumatoid arthritis are induced by IL-32.
Synonyms	IL-32, NK4, TAIF
Reference Data
Protein Families	Secreted Protein

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