Th Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Immunohistochemistry on frozen sections: 1:1000. Western Blot: 1:1000; detects a band of approximately 60kDa in rat caudate cell lysates. Immunofluorescence: 1:1000.
Reactivity	Mammalian, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Tyrosine hydroxylase purified from pheochromocytoma.
Specificity	This antibody is specific for Tyrosine hydroxylase (TH).
Isotype	IgG
Formulation	10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol State: Purified State: Liquid purified Ig
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	tyrosine hydroxylase
Database Link	Entrez Gene 25085 Rat UniProt ID P04177
Background	Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson
Synonyms	Tyrosine 3-hydroxylase, TYH
Reference Data

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