NALP1 (NLRP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 1 - 2 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Peptide corresponding to 13 amino acids near the carboxy-terminus of human NALP1
Specificity	This antibody detects NALP1 (CARD7).
Formulation	Phosphate Buffered Saline PBS containing 0.02% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	IgG Fractionation.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing.
Gene Name	NLR family, pyrin domain containing 1
Database Link	Entrez Gene 22861 Human UniProt ID Q9C000
Background	Death Effector Filament-forming Ced 4 like Apoptosis Protein (DEFCAP) is a novel apoptotic protein of the mammalian Ced 4 family. It has two isoforms: DEFCAP-Land DEFCAP-S. The deduced amino acid sequences of these two alternately spliced isoforms only differ by 44amino acids at the C-terminus. DEFCAP contains a caspase recruitment domain (CARD), a domain that with the proper stimulation can recruit caspases to form cytoplasmic structures called death effector filaments, which in turn initiate the apoptotic signaling pathway.
Synonyms	DEFCAP, KIAA0926, NAC, NALP1
Reference Data

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