PRDM5 (100-200) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1 - 3 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a portion of amino acids 100-200 of human PRDM5 protein.
Specificity	This antibody recognizes PR Domain Containing 5 (PRDM5).
Isotype	IgG
Formulation	PBS containing 0.2% Gelatin as stabilizer and 0.05% Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	PR domain 5
Database Link	Entrez Gene 11107 Human UniProt ID Q9NQX1
Background	PRDM5 is a transcription factor of the PR-domain protein family, and contains a PR-domain at the -NH2 terminus followed by 16 zinc finger motifs. It has been found to have a role in cell differentiation and tumorigenesis. A recombinant adenovirus expressing PRDM5 caused G2/M arrest and apoptosis upon infection of tumor cells. PRMD5 has been found to be silenced in breast, ovarian and lung cancers. The inactivation of PRDM5 may play a role in carcinogenesis.
Synonyms	PFM2
Note	Predicted Molecular Weight: 73 kDa.
Reference Data

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