Synaptotagmin 1 (SYT1) pSer309 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	Immunofluorescence: 1/100-1/200.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around phosphorylation site of Serine 309 (G-L-S(p)-D-P) derived from Human.
Specificity	The antibody detects endogenous level of Synaptotagmin only when phosphorylated at Serine 309.
Formulation	Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl State: Aff - Purified State: Liquid purified IgG fraction Stabilizer: 50% Glycerol Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~46 kDa
Gene Name	synaptotagmin 1
Database Link	Entrez Gene 20979 MouseEntrez Gene 25716 RatEntrez Gene 6857 Human UniProt ID P21579
Background	The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.
Synonyms	SYT1, SVP65, SYT, Synaptotagmin1, Synaptotagmin I, SytI, p65
Reference Data
Protein Families	Secreted Protein, Transmembrane

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