Cortisone Sheep Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA: 1.25μg/ml; 10 ng/ml cortisone produces 73% inhibition in a competitive ELISA, employing cortisone polyclonal antibody.
Host	Sheep
Clonality	Polyclonal
Immunogen	Cortisone-BTG
Specificity	This antibody reacts to Cortisone.
Isotype	IgG
Formulation	20mM Phosphate, 150mM Sodium Chloride, pH 7.2 containing 0.09% Sodium Azide as preservative State: Ig Fraction State: Liquid Ig fraction prepared by Caprylic Acid and Ammonium Sulphate precipitation procedures
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Background	Cortisone is a hormone. Chemically it is a corticosteroid with formula C21H28O5 and IUPAC name 17-hydroxy-11-dehydrocorticosterone. It is closely related to corticosterone. Cortisone and adrenaline are the main hormones released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response. Cortisone is the inactive precursor molecule of the active hormone cortisol. It is activated through hydroxylation of the 11-keto-group by an enzyme called 11-beta-steroid dehydrogenase. The active form cortisol is thus sometimes referred to as hydrocortisone. Cortisone is sometimes used as a drug to treat a variety of ailments.
Synonyms	17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione, 17alpha-Hydroxy-11-dehydrocorticosterone, 4-Pregnene-17alpha,21-diol-3,11,20-trione
Reference Data

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