EB3 (MAPRE3) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: 1/64000 (Detection Limit).  Western blot: 0.1-1.0 µg/ml. Approx 32kDa band observed in Human Brain (Cerebellum and Amygdala) and Mouse Brain lysates (calculated MW of 32kDa according to NP_036458.2).
Reactivity	Bovine, Canine, Human, Mouse
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence SGRLSNVAPPCILR, from the internal region of the protein sequence according to NP_036458.2.
Specificity	This antibody recognizes MAPRE3.
Formulation	Tris saline, 0.02% Sodium Azide, pH~7.3 with 0.5% BSA State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	microtubule associated protein RP/EB family member 3
Database Link	Entrez Gene 22924 Human UniProt ID Q9UPY8
Background	EB3 is a 282 amino acid homologue of EB1, a protein known to bind Adenomatous Polyposis Coli. It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.
Synonyms	End-binding protein 3, EB1 protein family member 3, RP3, EB3
Reference Data

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