Lmx1a Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA 1:1,000. Western blot 1:50 - 1:100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of mouse LMX1a.
Specificity	This antibody detects Lmx1a at center.
Isotype	Ig
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Gene Name	LIM homeobox transcription factor 1 alpha
Database Link	Entrez Gene 110648 Mouse UniProt ID Q9JKU8
Background	Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.
Synonyms	LMX1A, LIM homeobox transcription factor 1-alpha, LIM/homeobox protein LMX1A, LIM/homeobox protein 1.1, LMX-1.1
Note	Molecular weight: 42857 Da
Reference Data

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