IDE Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Peptide ELISA: 1/1,000. Western blot: 1/1000. Flow Cytometry: 1/10-1/50.  Immunohistochemistry: 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 406-435 amino acids from the Central region of human IDE.
Specificity	This antibody detects IDE at center.
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	insulin degrading enzyme
Database Link	Entrez Gene 3416 Human UniProt ID P14735
Background	IDE belongs to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
Synonyms	IDE, EC=3.4.24.56, Insulin protease, Insulinase, Insulysin, Abeta-degrading protease
Note	Molecular weight: 117838 Da
Reference Data

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