beta 2 Adrenergic Receptor (ADRB2) Rabbit Polyclonal Antibody
CAT#: AP13972PU-N
beta 2 Adrenergic Receptor (ADRB2) rabbit polyclonal antibody, Aff - Purified
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CNY 6314.00
货期*
                        2周
                    规格
                        | Cited in 1 publication. | 
Specifications
| Product Data | |
| Applications | IHC, WB | 
| Recommend Dilution | ELISA: 1/1,000. Western blot: 1/1,000. Immunohistochemistry on Paraffin sections: 1/10-1/50.  | 
        
| Reactivity | Human, Mouse | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to 236-264 amino acid residues surrounding S261 of human BAR2. | 
| Specificity | This antibody detetcs BAR2. | 
| Isotype | Ig | 
| Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide  | 
        
| Concentration | lot specific | 
| Purification | Protein A column, followed by peptide affinity purification. | 
| Conjugation | Unconjugated | 
| Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.  | 
        
| Gene Name | adrenoceptor beta 2 | 
| Database Link | |
| Background | Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. | 
| Synonyms | ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor | 
| Note | Molecular weight: 46459 Da | 
| Reference Data | |
Citations (1)
| The use of this Antibodies has been cited in the following citations: | 
|---|
| 
                                                Enhanced humoral immunity in mice lacking CB1 and CB2 receptors (Cnr1-/-/Cnr2-/- mice) is not due to increased splenic noradrenergic neuronal activity
                                                ,Simkins T, Crawford RB, Goudreau JL, Lookingland KJ, Kaplan BL,
                                                J Neuroimmune Pharmacol
                                                ,PubMed ID 24870806
                                                [ADRB2]
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